Category Archives: Weak Hydrogen Bonds

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New PCCP cover

New cover on PCCP! A work in collaboration with the Brooks H. Pate group in Virginia was featured as cover of PCCP in the July 28th issue. We show how transient chirality in the anesthetic sevoflurane is stabilized on formation of the dimer, as two different diastereoisomers (homochiral: left/left or right/right; heterochiral: left/right or right/left) are formed and distinguished by their spectral rotational signature. The structure of the dimers were fully resolved usign isotopic information, rendering information on the weak hydrogen bonds stabilizing the cluster.

PCCP cover sevo2sevo2


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PCCP cover

A work on the intermolecular cluster pyridine-methane in collaboration with the group of  Walther Caminati has been chosen as cover of PCCP. Methane behaves in the complex as a noble gas, binding on top of the aromatic ring. This T-shape structure contrasts with the in-plane structure of other pyridine clusters involving halomethanes.

portada_PCCP_pyr-CH4


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Sevoflurane···benzene

A work in collaboration with the Pate group in Virginia examined the weakly-bound cluster of sevoflurane···benzene ans was published in Angewandte Chemie. The primary interaction is a relatively strong C-H···pi hydrogen bond. The presence of additional C-H···F weak interactions hinders the six-fold symmetric internal rotation of benzene around sevoflurane. This is probably the first time that such a V6 barrier has been determined in a intermolecular complex.

sevo-benzene